Search results for "interaction [dark matter]"

Case-specific performance of MM-PBSA, MM-GBSA, and SIE in virtual screening.

2015

In drug discovery the reliable prediction of binding free energies is of crucial importance. Methods that combine molecular mechanics force fields with continuum solvent models have become popular because of their high accuracy and relatively good computational efficiency. In this research we studied the performance of molecular mechanics generalized Born surface area (MM-GBSA), molecular mechanics Poisson-Boltzmann surface area (MM-PBSA), and solvated interaction energy (SIE) both in their virtual screening efficiency and their ability to predict experimentally determined binding affinities for five different protein targets. The protein-ligand complexes were derived with two different app…

Tempting to Tag : An Experimental Comparison of Four Tagging Input Mechanisms

2010

Tagging helps achieve improved indexing and recommendation of resources (e.g., videos or pictures) in large data collections. In order to reap the benefits of tagging, people must be persuaded to label the resources they consume. This paper reports on a study in which four different tagging input mechanisms and their effect on users’ motivation to tag were compared. The mechanisms consisted of a standard tag input box, a chatbot-like environment, a bookmarking mechanism, and a “tag and vote” game. The results of our experiment show that the use of the nonstandard tagging input mechanisms does not affect users’ motivation to tag. In some instances tagging mechanisms were found to distract us…

Strong field phenomena: Atoms, Molecules, Nanostructures.

Life-based design as an extension of problem-based learning:A tool for understanding people and technology

2015

Global conditions are changing at such a rate that foreseeing trends in technological development, economic fluctuations and climatic conditions is ever more difficult. When developing technologies, there is one constant factor that practitioners and researchers should be aware of, and that is people. This is not to say that people, culture and social conditions remain stagnant, for these too evolve with the surrounding circumstances. Rather, appropriate tools and capabilities for investigating people, their lives and life situations, are integral to understanding what people need in terms of technology, how these technologies will be used, and more importantly how they will be valued in th…

Positioning the supply of live performances. Innovative managerial practices relating to the interaction of audience, performance and venue

2006

Because of an abundant offer of shows, the question of the cultural products positioning becomes increasingly crucial for the professionals of this sector. This article proposes to answer this strategic question by identifying original ways of differentiation in order to reinforce the identity of their offer. First of all, we insist on the need for analyzing the relation between the public and the spectacle (central road of positioning). We wish to highlight the various facets that structure this positioning. Then, we examine the interaction between the public and the cultural place (peripheral road of positioning). This tangible framework of consumption experiment can offer promising solut…

Intégrer des informations en escamots dans les textes techniques : quels effets sur les processus cognitifs ?

1998

Though computerized sytems now offer a wide range of options for accessing and displaying text or text-picture information, little is known about their effects on the user's cognitive processes. In this paper, we investigate the effect of a computer-specific display (pop-up window) which consists in displaying some pieces of information in windows that appear only under user's action. Experiments were carried out to compare the pop-up window device with other devices used on paper. The experiments dealt with text only as well as text-picture documents and involved various tasks. Results are discussed from a theoretical and a practical point of view.

Bodily expressions of dominance in children's reasoning : an analysis of multimodal and sociometric data

2015

This case study explores how two Hungarian children argue for their choices in a decision- making task in which they were asked to pick objects useful on a deserted island. The study involves an analysis of the multimodal data of the video-recorded tasks, carried out as pair-work, and sociometric background data that were collected in order to build an initial understanding of the participants’ social relations. The aim of the study is to discover how dominance relations manifest in bodily acts during reasoning. Results show that dominance was expressed by specific embodied strategies such as by taking away objects or replacing them, and that the bodily gestures were closely intertwined wit…

Development of silent reading fluency and reading comprehension across grades 1 to 9 : unidirectional or bidirectional effects between the two skills?

2022

Purpose This study examines the developmental interplay between silent reading fluency and reading comprehension from Grade 1 to Grade 9 (age 7 to 15) in a large Finnish sample (N = 2,518). Of particular interest was whether the associations are bidirectional or unidirectional. Methods Children’s silent reading fluency and reading comprehension skills were assessed using group-administered tests, at seven time points, in Grades 1, 2, 3, 4, 6, 7, and 9. A random intercept cross-lagged panel model with latent factors was used to identify between- and within-person associations between silent reading fluency and reading comprehension. The use of latent factors allowed for the controlling of me…

miMic

2016

miMic, a sonic analogue of paper and pencil is proposed: An augmented microphone for vocal and gestural sonic sketching. Vocalizations are classified and interpreted as instances of sound models, which the user can play with by vocal and gestural control. The physical device is based on a modified microphone, with embedded inertial sensors and buttons. Sound models can be selected by vocal imitations that are automatically classified, and each model is mapped to vocal and gestural features for real-time control. With miMic, the sound designer can explore a vast sonic space and quickly produce expressive sonic sketches, which may be turned into sound prototypes by further adjustment of model…

Scaffolding adult immigrant students in an EFL lesson

2012

Oppimisprosessi on luonteeltaan enemmänkin sosiaalinen kuin yksilöllinen. Tämä lähestymistapa on hyödyllinen myös aikuisille maahanmuuttajaopiskelijoille, koska sosiokulttuuriseen näkemykseen perustuvassa oppimisympäristössä he oppivat sekä oppiainetta että perehtyvät yhteiskunnan kulttuuriin, johon he sopeutuvat turvallisessa ja kannustavassa ympäristössä muiden seurassa. Sosiokulttuurisen teorian mukaan oppiminen on opettajan ja opiskelijoiden välisen vuorovaikutuksen seuraus, joka tapahtuu opiskelijoiden lähikehityksen vyöhykkeellä (the zone of proximal development, ZPD). Lähikehityksen vyöhyke on oppimisen todellisen kehitystason ja potentiaalisen kehitystason välinen ero. Toisin sanoen…